Niacin and melatonin have a unique effect on adiponectin, a peptide secreted by fat cells that plays a role in obesity-related diseases and has a direct action on the liver, skeletal muscle and vasculature
Niacin helped reduce obesity in an animal model and in one pilot study reduced abdominal fat by an average of 27% in participants; melatonin deficiency also correlates with obesity, and supplementation has led to significant weight loss in treatment groups
Niacin can reduce pro-inflammatory cytokine expression and has an anti-inflammatory effect, properties which some experts believe may help reduce the severity of COVID-19
Melatonin influences circadian rhythm and the immune system; it also reduces inflammation and is an antioxidant; one group of scientists called it a "silver bullet" in treating COVID-19 patients
Read the full analysis by Dr. Mercola
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