Researchers found an association between vitamin D and leptin levels. The hormone leptin is secreted by fat cells in proportion to fat deposits, signaling the hypothalamus to regulate energy balance
Researchers have found those with nonalcoholic fatty liver disease (NAFLD) often present with vitamin D deficiency; however, the research into supplementation is not consistent, potentially because supplement doses are not high enough to affect a change
Vitamin D is metabolized in the liver and undergoes further hydroxylation in the kidney, producing 1,25 dihydroxyvitamin D3, upregulating a transcription factor used to reduce reactive oxygen species and decrease cellular aging
Vitamin D insufficiency is linked to several negative health conditions, including cancer and cardiovascular disease. While it is best to optimize vitamin D levels with safe sun exposure, if you find supplementation is necessary after a serum vitamin D test, also supplement with magnesium and vitamin K2 (MK-7)
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