For those at high risk, colonoscopies may be useful, but it’s important to weigh the potential benefits against the potential harms
In one study, those who were invited to get colonoscopies had an 18% lower risk of colorectal cancer than the unscreened group, but there was no statistically significant reduction in the risk of death from colorectal cancer
One analysis found a death rate of 3 per 100,000 colonoscopies, along with serious adverse events in 44 per 10,000, “with a number needed to harm of 225”
Other risks include bleeding after removal of a precancerous polyp, perforation and anesthesia complications
To avoid contaminated equipment, contact the clinic or hospital ahead of time to find out about sterilization procedures; you’re looking for a hospital that uses peracetic acid — not glutaraldehyde (Cidex) — to sterilize its flexible endoscopes
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